The ReGenFix procedure actively contributes to pioneering research!

Here you can find the published articles where ReGenFix was applied. Our technology allowed for maintaining an unaltered resolution and reproducibility over the experimental replicates and with the same chromatography column.

If you use ReGenFix to standardize your columns for experimental research, please cite us in your Methods section: The ReGenFix procedure ( has been used to standardize and calibrate the chromatography columns“.

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Cocco E, Farci D, Guadalupi G, Manconi B, Maxia A, Piano D. The elongation factor 1-alpha as storage reserve and environmental sensor in Nicotiana tabacum L. seeds. Plant Sci. 2024 May 8;345:112113. doi: 10.1016/j.plantsci.2024.112113.

Farci D, Milenkovic S, Iesu L, Tanas M, Ceccarelli M, Piano D. Structural characterization and functional insights into the type II secretion system of the poly-extremophile Deinococcus radiodurans. J Biol Chem. 2024 Feb;300(2):105537. doi: 10.1016/j.jbc.2023.105537.


Fantuzzi A, Haniewicz P, Farci D, Loi MC, Park K, Büchel C, Bochtler M, Rutherford AW, Piano D. Bicarbonate activation of the monomeric photosystem II-PsbS/Psb27 complex. Plant Physiol. 2023 Aug 3;192(4):2656-2671. doi: 10.1093/plphys/kiad275.

Farci D, Graça AT, Iesu L, de Sanctis D, Piano D. The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans. J Biol Chem. 2023 Jan;299(1):102784. doi: 10.1016/j.jbc.2022.102784.


Farci D, Haniewicz P, Piano D. The structured organization of Deinococcus radiodurans‘ cell envelope. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2209111119. doi: 10.1073/pnas.2209111119.

Farci D, Haniewicz P, de Sanctis D, Iesu L, Kereïche S, Winterhalter M, Piano D. The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions. J Biol Chem. 2022 Jun;298(6):102031. doi: 10.1016/j.jbc.2022.102031.

Farci D, Cocco E, Tanas M, Kirkpatrick J, Maxia A, Tamburini E, Schröder WP, Piano D. Isolation and characterization of a main porin from the outer membrane of Salinibacter ruber. J Bioenerg Biomembr. 2022 Dec;54(5-6):273-281. doi: 10.1007/s10863-022-09950-7.


Farci D, Kereïche S, Pangeni S, Haniewicz P, Bodrenko IV, Ceccarelli M, Winterhalter M, Piano D. Structural analysis of the architecture and in situ localization of the main S-layer complex in Deinococcus radiodurans. Structure. 2021 Jul 12:S0969-2126(21)00249-5. doi: 10.1016/j.str.2021.06.014.